- ADAPTIVE CRT
The purpose of this study is to show that Adaptive CRT is at least as good at optimizing a patient's cardiac resynchronization therapy (CRT) as the current method of using an echocardiogram.
- ANALYZE ST
The intent of this study is to demonstrate the safety and effectiveness of the ST Monitoring Feature in the Fortify® ST ICD system (or other Implantable Cardioverter Defibrillator (ICD) systems with the ST Monitoring Feature).
- BLOCK CTI
The purpose of the BLOCk-CTI study is to evaluate the safety and effectiveness of the Blazer® Open-Irrigated Ablation Catheter for the treatment of sustained or recurrent type 1 atrial flutter.
- BRILINTA AD HOC PCI
The purpose of this study is to assess the pharmacodynamic effect of ticagrelor in ACS patients undergoing an Ad Hoc PCI.
The purpose of the trial is to evaluate the wireless monitoring of pulmonary artery pressure using the CardioMEMS HF Pressure Measurement System in adult subjects with NYHA Class III Heart Failure.
- ENGAGE AF
This study is to demonstrate the safety and efficacy profile, in two different dose regimens of Edoxaban (DU-176b), (an investigational new drug being tested for the prevention of stroke/systemic embolic events (SEE)), in individuals with atrial fibrillation.
The purpose of this study is to compare the effects of ticagrelor and clopidogrel in patients with Peripheral Artery Disease.
- EVOLVE II
The purpose of this study is to assess the safety and effectiveness of the SYNERGY Everolimus-Eluting Platinum Chromium Coronary Stent System for the treatment of subjects with atherosclerotic lesion(s) = 34 mm in length (by visual estimate) in native coronary arteries =2.25 mm to =4.0 mm in diameter (by visual estimate).
The objective of this study is to confirm the long-term safety and reliability of the Linox Lead System as used with BIOTRONIK ICDs.
- IMPROVE IT
This is a randomized, active-control, double-blind study of subjects with stabilized high-risk acute coronary syndrome (ACS).