Oral-Facial-Digital Syndrome

National Organization for Rare Disorders, Inc.

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It is possible that the main title of the report Oral-Facial-Digital Syndrome is not the name you expected.

Disorder Subdivisions

  • None

General Discussion

Oral-facial-digital syndrome (OFDS) is an umbrella term for at least 10 apparently distinctive genetic disorders that are characterized by defects and flaws in the development of the structure of the oral cavity including the mouth, tongue, teeth, and jaw; the development of the facial structures including the head, eyes, and nose; and the fingers and toes (digits); along with differing degrees of mental retardation. The presentation of signs and symptoms is extremely varied, making diagnosis difficult. OFDS type I is the most common of all of these disorders, and it is quite rare. Each of the other types is extremely rare.

Supporting Organizations


PO Box 751112
Las Vegas, NV 89136
Tel: (702)769-9264
Fax: (702)341-5351
Tel: (888)486-1209
Email: info@ameriface.org
Website: http://www.ameriface.org

Children's Craniofacial Association

13140 Coit Road
Suite 517
Dallas, TX 75240
Tel: (214)570-9099
Fax: (214)570-8811
Tel: (800)535-3643
Email: contactCCA@ccakids.com
Website: http://www.ccakids.com

FACES: The National Craniofacial Association

PO Box 11082
Chattanooga, TN 37401
Tel: (423)266-1632
Fax: (423)267-3124
Tel: (800)332-2373
Email: faces@faces-cranio.org
Website: http://www.faces-cranio.org

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
Website: http://rarediseases.info.nih.gov/GARD/

Let's Face It

University of Michigan, School of Dentistry / Dentistry Library
1011 N. University
Ann Arbor, MI 48109-1078
Tel: (360)676-7325
Email: faceit@umich.edu
Website: http://dent.umich.edu/


333 East 30th Street, Lobby Unit
New York, NY 10016
Tel: (212)263-6656
Fax: (212)263-7534
Email: info@myface.org
Website: http://www.myface.org

NIH/National Institute of Dental and Craniofacial Research

Building 31, Room 2C39
31 Center Drive, MSC 2290
Bethesda, MD 20892
Tel: (301)496-4261
Fax: (301)480-4098
Tel: (866)232-4528
Email: nidcrinfo@mail.nih.gov
Website: http://www.nidcr.nih.gov/

National Foundation for Ectodermal Dysplasias

6 Executive Drive
Suite 2
Fairview Hights, IL 62208
Tel: 618-566-2020
Fax: 618-566-4718
Email: info@nfed.org
Website: http://www.nfed.org

National Foundation of Dentistry For the Handicapped

1800 15th Street
Suite 100
Denver, CO 80202
Tel: (303)534-5360
Fax: (303)534-5290
Email: emorris@nfdh.org
Website: http://www.nfdh.org

Prescription Parents

22 Ingersoll Road
P.O. Box 920554
Wellesley, MA 2181
Tel: (617)499-1936
Email: info@prescriptionparents.org
Website: http://www.prescriptionparents.org

The Arc

1825 K Street NW, Suite 1200
Washington, DC 20006
Tel: (202)534-3700
Fax: (202)534-3731
Tel: (800)433-5255
Email: info@thearc.org
Website: http://www.thearc.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

Last Updated:  9/23/2007
Copyright  2007 National Organization for Rare Disorders, Inc.