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Home > Patient & Family Resources > Health Library > Typhoid Vaccines: What You Need to Know
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IMPORTANT NOTICE: COVID-19 testing appointments are not available at Cone Health emergency departments or urgent care locations. Click here for testing options.
Typhoid vaccine can prevent typhoid fever.
People who are actively ill with typhoid fever and people who are carriers of the bacteria that cause typhoid fever can both spread the bacteria to other people. When someone eats or drinks contaminated food or drink, the bacteria can multiply and spread into the bloodstream, causing typhoid fever.
Typhoid fever can be a life-threatening disease. Symptoms of infection include persistent high fever, weakness, stomach pain, headache, diarrhea or constipation, cough, and loss of appetite.
People who do not get treatment can continue to have fever for weeks or months. As many as 30% of people who do not get treatment die from complications of typhoid fever. There are fewer antibiotic treatment options as drug-resistant typhoid bacteria has become more common in many parts of the world.
Typhoid fever is common in many regions of the world, including parts of East and Southeast Asia, Africa, the Caribbean, and Central and South America. Typhoid fever is not common in the United States.
There are two vaccines to prevent typhoid fever. One is an inactivated (killed) vaccine and the other is a live, attenuated (weakened) vaccine. Your health care provider can help you decide which type of typhoid vaccine is best for you.
Routine typhoid vaccination is not recommended in the United States, but typhoid vaccine is recommended for:
Typhoid vaccine may be given at the same time as other vaccines.
Tell your vaccine provider if the person getting the vaccine:
In some cases, your health care provider may decide to postpone typhoid vaccination to a future visit.
People with minor illnesses, such as a cold, may be vaccinated. People who are moderately or severely ill should usually wait until they recover before getting typhoid vaccine.
Your health care provider can give you more information.
People sometimes faint after medical procedures,
including vaccination. Tell your provider if you feel
dizzy or have vision changes or ringing in the ears.
As with any medicine, there is a very remote chance
of a vaccine causing a severe allergic reaction, other
serious injury, or death.
An allergic reaction could occur after the vaccinated person leaves the clinic. If you see signs of a severe allergic reaction (hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, or weakness), call 9-1-1 and get the person to the nearest hospital.
For other signs that concern you, call your health care provider.
Adverse reactions should be reported to the Vaccine Adverse Event Reporting System (VAERS). Your health care provider will usually file this report, or you can do it yourself. Visit the VAERS website at www.vaers.hhs.gov or call 1-800-822-7967.VAERS is only for reporting reactions, and VAERS staff do not give medical advice.
Vaccine Information Statement
Department of Health and Human Services
Centers for Disease Control and Prevention
Many Vaccine Information Statements are available in Spanish and other languages. See www.immunize.org/vis.
Hojas de información sobre vacunas están disponibles en español y en otros idiomas. Visite www.immunize.org/vis.
Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
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